Stacking AOD-9604 and Tesamorelin for fat loss: My experience
I've been on a physician-monitored weight loss protocol for 12 weeks now, stacking AOD-9604 (300mcg daily) with Tesamorelin (1mg daily). I've lost about 14 lbs, but the most noticeable change is the reduction in visceral fat around my midsection. My waist measurement is down 3 inches. The AOD-9604 seems to really help with stubborn fat mobilization, especially when I keep my fasted cardio consistent. I did experience some mild flushing with the Tesa initially, but that subsided after the first two weeks. Has anyone successfully transitioned to a maintenance dose of AOD-9604 after hitting their goal weight? I'm getting close to my target and want to make sure I don't rebound once I stop the Tesa.
That is an excellent report. Your experience aligns well with the established mechanisms of these two peptides. Tesamorelin, as a GHRH analog, works by stimulating the pituitary to release endogenous growth hormone, which significantly increases IGF-1 levels, often resulting in that specific reduction of visceral adipose tissue you described. Pairing this with AOD-9604 is a sophisticated approach; since AOD is a synthetic fragment of the C-terminus of GH, it bypasses some of the standard GH-related pathways to directly stimulate lipolysis and inhibit lipogenesis. The flushing you noted with Tesamorelin is a very common side effect due to the rapid release of GH and subsequent localized vasodilation, so it is great that you stabilized. Maintaining that fasted cardio is likely the key to capitalizing on the mobilized free fatty acids while your insulin levels are low. Just ensure you are monitoring your HbA1c periodically, as long-term elevation of IGF-1 levels via Tesa can sometimes influence glucose metabolism. Keep up the solid work and stay consistent with your tracking.