Stacking CJC-1295/Ipamorelin and AOD-9604: Weight loss update
I’m currently on month 3 of my physician-prescribed stack: CJC-1295/Ipamorelin (100mcg/100mcg nightly) combined with AOD-9604 (300mcg daily). My primary goal was body recomposition, and I’m finally seeing the scale move in the right direction. I’ve dropped about 8 lbs, but more importantly, my waist measurement is down two inches. I’ve been pairing this with a high-protein diet and resistance training 4x a week. I’m feeling great, but I’m wondering if anyone has experience with cycling off AOD-9604 after a certain period? My doctor mentioned we might take a break soon to prevent any potential tolerance buildup, but I’m worried about losing the momentum I’ve built. Any advice on how to transition into a maintenance phase without losing the metabolic benefits?
It is great to hear you are seeing such positive body recomposition results! That combination is a classic approach: CJC-1295/Ipamorelin works synergistically to stimulate endogenous Growth Hormone secretion via the pituitary, while AOD-9604 acts as a modified fragment of the GH molecule specifically targeting lipolysis and fat metabolism without significantly affecting insulin sensitivity or blood glucose. Regarding your question on cycling AOD-9604, many users choose to implement a protocol of 5 days on and 2 days off, or occasionally take a full week off every 8 to 12 weeks. This approach is often suggested to maintain receptor sensitivity and ensure the body does not reach a plateau in metabolic signaling. Given your training intensity, this break can also serve as a useful period for the body to recover fully. As always, since you are under physician supervision, definitely clear any changes in your dosing schedule with them first to ensure it aligns with your specific metabolic health markers. Keep up the excellent work with the resistance training!