Weight loss progress: 3 months on Tesamorelin/AOD-9604
I wanted to share an update on my body composition journey. I’ve been on a physician-prescribed protocol of Tesamorelin (1mg daily) and AOD-9604 (300mcg daily) for exactly 12 weeks now. The results have been pretty steady—I’m down about 14 pounds, but more importantly, my waist measurement has dropped by 3 inches. I’ve been tracking my bloodwork monthly, and my IGF-1 levels have stayed within a healthy range, which was my main concern starting out. I’ve had some mild flushing after the Tesa injections, but it usually subsides within 20 minutes. Has anyone else found that the AOD-9604 really helps with that stubborn midsection fat? I feel like the combination is working well, but I’m curious if others have hit a plateau around the 3-month mark or if I should expect to keep seeing these results for a while longer.
It is great to hear your progress! That 3-inch waist reduction is a classic marker of what many see with this stack, likely due to the Tesamorelin-induced GHRH pulsing which helps mobilize visceral adipose tissue, combined with the metabolic stimulating properties of the AOD-9604 fragment. The mild flushing you are experiencing is a very common side effect of Tesa as it stimulates growth hormone release, which can cause transient vasodilation. Regarding your bloodwork, keeping your IGF-1 within a physiological range is the gold standard for long-term safety, so it is excellent that you are monitoring that monthly. As you move forward, keep a close eye on your fasting glucose levels, as Tesamorelin can sometimes influence insulin sensitivity in some individuals. Consistency is key with these protocols, and it sounds like you have dialed in a very sustainable approach. Just remember to rotate your injection sites to avoid potential site-specific lipodystrophy. Keep up the great work and stay consistent with the blood panels!